|
KMID : 0881720190340030242
|
|
Journal of Food Hygiene and Safety
2019 Volume.34 No. 3 p.242 ~ p.250
|
|
|
Development of a Simultaneous Analytical Method for Determination of Herbicide Fenquinotrione and KIH-3653-M-2 Residues in Agricultural Crops using LC-MS/MS
|
|
Park Ji-Su
Do Jung-Ah
Lee Han-Sol
Cho Sung-Min
Shin Hye-Sun
Jang Dong-Eun
Jung Yong-Hyun
Lee Kang-Bong
|
|
|
Abstract
|
|
|
|
An analytical method was developed for the determination of fenquinotrione, a triketone herbicide, in agricultural products. Fenquinotrione was metabolized to KIH-3653-M-2 in plants. Analyte extraction was conducted using 2% formic acid in acetonitrile and cleaned up using a hydrophillic-lipophillic balance (HLB) cartridge. The limits of detection (LOD) and quantification (LOQ) were 0.004 and 0.01 mg/kg, respectively. Matrixmatched calibration curves were linear over the calibration ranges (0.001~0.1 μg/mL) into a blank extract with r 2 >0.99. The recovery results for fenquinotrione and KIH-3653-M-2 ranged between 81.1 to 116.2% and 78.0 to 110.0% at different concentration levels (LOQ, 10×LOQ, 50×LOQ) with relative standard deviation (RSD) less than 4.6%. All values were corresponded with the criteria ranges requested in both the Codex (CAC/GL 40-1993, 2003) and MFDS guidelines (2016). Therefore, the proposed method can be used as an official analytical method for determination of fenquinotrione in the Republic of Korea.
|
|
|
KEYWORD
|
|
|
Fenquinotrione, Fenquinotrione metabolite, LC-MS/MS, Herbicide, Analytical method, Agricultural product
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|